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A subset of these samples (97) underwent low-depth-of-coverage whole-genome sequencing.In total, 16% of colorectal carcinomas were found to be hypermutated: three-quarters of these had the expected high microsatellite instability, usually with hypermethylation and MLH1 silencing, and one-quarter had somatic mismatch-repair gene and polymerase ε (POLE) mutations.Most investigators divide CRC biologically into those with microsatellite instability (MSI; located primarily in the right colon and frequently associated with the Cp G island methylator phenotype (CIMP) and hyper-mutation) and those that are microsatellite stable but chromosomally unstable.A rich history of investigations (for a review see ref.Integrative analyses suggest new markers for aggressive colorectal carcinoma and an important role for MYC-directed transcriptional activation and repression..We now present results from multidimensional analyses of human colorectal carcinoma (CRC).

The specific numbers of samples analysed by each platform are shown in Supplementary Table 1.

The following degrees were conferred: in person Doctor of Medicine DOWNING COLLEGE Phillips, Mary Louise Smellie, William James Buchanan NEWNHAM COLLEGE Frith, Peggy Alison in absence Doctor of Medicine FITZWILLIAM COLLEGE Pratt, Guy Edward Dickens in person Doctor of Science DARWIN COLLEGE Clack, Jennifer Alice in absence Doctor of Science GONVILLE AND CAIUS COLLEGE Bowsher, David Richard in person Doctor of Letters CLARE COLLEGE Cressy, David Arthur in absence Master of Arts [Grace 4 of 9 December 2000] Set, Patricia Ai Khoon Associate Lecturer in the Faculty of Clinical Medicine KING'S COLLEGE in person Doctor of Philosophy Bass, Sarah Jane Murphy, Fionnuala Catherine Stevens, Christopher John White, Peter James in absence Master of Philosophy Helgoe, Camilla Tveteraas Reynolds, Margaret Philpott Ray Weeks, Alice Rebecca TRINITY COLLEGE in person Doctor of Philosophy Cox, Anthony Roger Wilson Evans, Carlton Anthony William Flynn, Paul Desmond Kam, Alvin Harvey Siew Wah Mosley, Adam John Ruszkowski, Mateusz Sawon, Justin Thomas, David Stephen Wilman, Richard John Master of Arts Bleehen, Robert Edward Bleehen, Stanley Sholom Daley, Howard Martin Ockenden, James Edward Master of Philosophy Bailey, Dominic Timothy John Silver, Geoffrey Leong in absence Doctor of Philosophy Hunt, Tristram Julian William Knox, Andrea Lesley Wright, Edward Andrew Master of Arts Brown, Stephen Francis Maurice Hunt, Tristram Julian William Travis, Michael James Master of Philosophy Allcock, Jeremy Thomas Raphael Clive Endersby, James John Bachelor of Arts Damerell, David John Stokes ST JOHN'S COLLEGE in person Doctor of Philosophy Brouwer, René Roel Dymond, David Percy Faulkner, Paul Anthony Fuller, Dorian Gergely, Vladimir Gurnell, Mark Kim, Ji Seon Varden, Erik Master of Philosophy Brand, Mark Richard Koch, Damaris Tonja Neuert, Veronika O'Shea, Niall Anthony Patrick in absence Doctor of Philosophy Fu, Gangzhan Mc Dowell, Richard William Master of Philosophy Loddo, Kim Lourdes Sampath, Srihari Cidambi PETERHOUSE in person Master of Studies Carmichael, Emma Rutherford in absence Master of Arts Poole, Selvwyn Giraldus Master of Philosophy Schaefer, Joshua James CLARE COLLEGE in person Doctor of Philosophy Baldwin, Peter John Kleist, Aaron J Morris, Emma Catherine Shipp, Richard Michael Smith, Katharine Emma Master of Philosophy Graham, Michele Dion Pinkus, Susanna Joy in absence Doctor of Philosophy Leask, David Matthew Pitt, Catherine Erica Thomson, Bridget Jane Yao, Cheong Chuen Master of Arts Deeley, Peter Quinton Master of Philosophy Foulkes, Risha Kostin Takano, Takako PEMBROKE COLLEGE in person Doctor of Philosophy Barnard, Anne Mary Louise Ingram, Esther Margaret Li, Sheng Feng Master of Philosophy Dent, Jonathan William in absence Master of Arts Barclay, Peter Roger Butler-Cole, Benjamin Falcon Clarke Master of Philosophy Milford, Claire Emily GONVILLE AND CAIUS COLLEGE in person Doctor of Philosophy Urban, Christian in absence Doctor of Philosophy Botley, Paul Alan Kirsch, Ralf Dietrich TRINITY HALL in person Doctor of Philosophy De Grey, Aubrey David Nicholas Jasper Piechnik, Stefan Kazimerz Vermeren, Matthieu M CORPUS CHRISTI COLLEGE in person Doctor of Philosophy Bethel, Nicolette Ruth Marie Griffin, Miranda Helen Towheed, Syed Shafquat Yeo, Wei Wei Master of Philosophy O'Regan, Tarik Hamilton in absence Doctor of Philosophy Prodigalidad, Michael Warusawithana Kulatilake, Samanti Dineshkumari Master of Arts Fishwick, Nigel Meade, Nicholas Master of Philosophy Barker, Roger Martin QUEENS' COLLEGE in person Doctor of Philosophy Breckenridge, Ross Alexander Grig, Lucy Hannah Charlotte Humphries, Alexander Charles in absence Doctor of Philosophy Flanigan, Barry John Van Es, Bart Bastiaan Master of Philosophy Daly, Colleen Elizabeth Van Es, Bart Bastiaan ST CATHARINE'S COLLEGE in person Doctor of Philosophy Kirkden, Richard David Master of Philosophy Ward, Sally Jane in absence Doctor of Philosophy Mearns, Robin John Master of Arts Donnelly, Sandra Ann Master of Philosophy Palmer, Jennifer Lynne Sohn, Jooyoung JESUS COLLEGE in person Doctor of Philosophy Castle, Elizabeth Anne Freud-Kandel, Miriam Judith Fyfe, Aileen Kennedy Master of Arts Freud-Kandel, Miriam Judith Master of Philosophy Castle, Elizabeth Anne Kennish, Yolanda Christina Stokes, Kaele Leanne MAGDALENE COLLEGE in absence Master of Arts Abbott, Mark Barrington Master of Philosophy De Souza, Nigel Andrew Moyo, Moses EMMANUEL COLLEGE in person Doctor of Philosophy Barnard, Jonathan Andrew Jiggins, Francis Michael Leggate, Daniel Richard Miquel, Marc Eric Wheeler, Paul John Master of Arts Agble, Ronald Kojo Eweonam Anderson, Sara Elizabeth Arch, Rachel Elizabeth Baker, Wayne Hafford Ball, Stephen Martyn Joseph Bennett, Jemima Charlotte Benson, Margaret Victoria Bullen, Samuel David Burton, Ashok Ashley Cannock, Giles Michael Morgan Chew, David Robert Clayton, Jenny Natasha Clements, Andrew Russell Niel Critchley, Robert Andrew Darley, Kathryn Louise Davenport, Liam Andrew Davies, Victoria Anne Dhanjal, Regpal Dineen, Richard Martin Dolman, Catherine Ellen Douglas, Roger Bruce Ellis, Christian James Ellis, Joanna Lesley Fagg, George Stephen Ferguson, Andrew James Ford, Stuart Duncan Gibbs, Martin Richard Gover, Gillian Constance Gower, Timothy James Griffiths, Katherine Siân Haines, Christopher Paul Hall, Caroline Joanne Hamour, Sally Mohamed Abdelaal Harding, Gregory John Hardingham, Neil Robert Harris, Alistair James Heawood, Jonathan Paul Cree Hewitt, Frank Alexander Hodson, Elizabeth Jane Hunt, Stefan Alexis James, Rachel Anne Jiggins, Francis Michael Jones, Richard Graham Kelly, Edward Gerald Kennedy, Nicole Elizabeth Leggate, Daniel Richard Lloyd, Claire Rebecca Maclennan, John Campbell Mallett, Clare Mayes, Alasdair Charles Brett Mock, Vanessa Dunya Moore, Ian Christopher Moran, Cassandra Judith Abigail Munro, Christopher Hamish Nilson, Peder Erling O'Brien, Edmund Andrew Mark Palmer, Matthew Blake Peltz, Elizabeth Helen Pickett, Alison Jayne Prabhu, Ashutosh Harshawardhan Sudhakar Reay, David Browell Reay, Kasia Anna Richardson, Peter Riseley, Mark James Scales, Antoinette Schluppeck, Denis Senior, Timothy Vincent Sjolin, Catarina Marianne Slack, Kevin John Smith, Justin Steven Barrie Tench, Kate Mirren Thompson, Jennifer Helen Todd, Catherine Triggs, Robert James Alexander Wakeford, Thomas Henry Guy Watson, Sally Jane Whetman, James Benet Williams, Emily Jane Wilson, Alastair James Wise, Elspeth Mary in absence Master of Arts Albuquerque, Joao Portela Gomes Booth, Daniel Robin Boucherat, Fabrice Gil Butchart, Joseph William Collins, Louise Michele Constable, Nina Rose Crane, Richard Francis De Bellaigue, Christina Alix Melisande Dennis, Flora Marian Doble, Jane Ann Evans, Gwynfor Owen Hollowood, Christopher John Jackson, Matthew Lee, Michael James Kimsen Mac Donald, Nathan Mc Hale, Stephen Nugent, Claire Randle, Jonathan Thomas Raphael, Anna Nancy Spencer, Sarah-Jane Thomaidis, Thomas-Nikitas Trevithick, Mark Thomas Master of Philosophy O'Loghlen, John Joseph SIDNEY SUSSEX COLLEGE in person Doctor of Philosophy Mahon, Piers Seaburne Macmahon Master of Philosophy Sood, Poornima in absence Doctor of Philosophy Lalam, Sree Harsha Master of Philosophy James, Sarah Pritchard, Matthew Callum DOWNING COLLEGE in person Doctor of Philosophy Oeckl, Robert Master of Arts [Grace 2 of 9 December 2000] Barrand, Margery Ann Fellow of Downing College Master of Philosophy Awuku-Asamoah, Abena Ampomea Kitson, Peter Michael Nunez de la Mora, Alejandra in absence Doctor of Philosophy Kwong, Oi Yee Master of Philosophy Dimova, Rozita GIRTON COLLEGE in person Doctor of Philosophy Sharp, Carla NEWNHAM COLLEGE in absence Doctor of Philosophy Herrington, Eldrid Roberts Jennings, Victoria Jane SELWYN COLLEGE in person Doctor of Philosophy Haydon, Sarah Katherine Johnston, Gordon Mark Wright, Stewart Andrew Master of Philosophy Jones, Stephen Michael Novoa-Cain, Mauricio Alfredo Williams, Richard John Master of Business Administration Zhang, Ting Katherine Bachelor of Arts and Master of Natural Sciences Brown, Andrew George in absence Master of Philosophy Weiss, Cynthia Miriam FITZWILLIAM COLLEGE in absence Doctor of Philosophy Ali, Ihsan Brecher, Dominic Raphael Master of Arts Hidle, John David CHURCHILL COLLEGE in person Doctor of Philosophy Khorsheed, Mohammad Soliman Medlock, Jonathan Alan Stacey, Adrian James Master of Arts Stacey, Adrian James Master of Philosophy Gong, Belvin Welply, Oakleigh Elizabeth in absence Doctor of Philosophy Dharmawardana, Kahanawita Gamaethiralalage Padmapani Master of Arts Simkins, Stephen Master of Philosophy Sogard, Jeffrey William Wilson, Siobhan Deire Wiysonge, Charles Shey Umara Wynne-Jones, Stephanie Anne Yaron, Hadas NEW HALL in person Master of Philosophy Chanda, Casmir DARWIN COLLEGE in person Doctor of Philosophy Blackburn, John Francis Freestone, Sarah Helen Goswami, Tapasree Guest, Paul Martin Martoglio, Ann-Marie Master of Philosophy Chan, Carmen Erskine, Susan Hayley Hussey, Christopher James Kaptoge, Stephen Kipkemoi Kpodo, Frances-Yvonne Lam, Daniel King Wai Margari, Vasiliki Petropoulou, Maria in absence Master of Philosophy Ho, Dennis Hin-Li Joo, Iroo Stobbs, Jason Edward WOLFSON COLLEGE in person Doctor of Philosophy Chang, Yu-Wen Charlene Kauer, Matthias Rose, Felicity Clare Sheppard, Leyland Curtis Master of Arts [Grace 3 of 9 December 2000] Gonzalez, Maria Isabel Fellow of Wolfson College Master of Philosophy Day, Alexander William Knauf, Christopher Wade Millard, Bernard Richard Park, Koo Woong in absence Doctor of Philosophy Dawson, Mark Stanley Sargeant, Lincoln Alexander Master of Philosophy Campbell, Neil James Morita, Masayasu Master of Studies Topp, Christian Oliver CLARE HALL in person Doctor of Philosophy Clifford, David John Harold in absence Doctor of Philosophy Garro-Martinez, Nuria ROBINSON COLLEGE in person Doctor of Philosophy Kleinsorge, Britta Yvonne Zeffman, Amanda Tracey Master of Philosophy Mac Coll, Allan William in absence Master of Arts Francis, James Charles Trethowan LUCY CAVENDISH COLLEGE in person Master of Philosophy Baylon, Maria Lourdes Lising Kagiadaki, Maria ST EDMUND'S COLLEGE in person Doctor of Philosophy BY INCORPORATION [Grace 1 of 9 December 2000] Blyth, Caroline Mary Fellow of St Edmund's College, Doctor of Philosophy of the University of Oxford Doctor of Philosophy Correia Guedes, Manuel de Arriaga Brito O'Dochartaigh, Caitriona Aine in absence Master of Philosophy Cauthery, David Harald Gobel, Christian Helmut Hanley, Ryan Patrick HUGHES HALL in absence Master of Philosophy Balgobin, Stanley Ethan Chaudhri, Yumna Shamim Shigenaga, Tatsuya T.

College student Jennifer Kaye Ringley turns on her "Jenni Cam" for the first time and begins uploading pictures of herself to the web.

The site, however, became far more than an academic exercise, attracting up to 4 million hits a day at its peak. C., in 1998, Ringley added three more webcams and began charging through Pay Pal for "premium" access to more-frequent image uploads.

Earning her living from the site, Ringley emerged as a web-empowered cult of personality.




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It wasn’t going to show up in the Event Receivers collection for that list instance, because it was associated to the list type.